Manufacturing Facility – Set-Up for Success

Cannabis Consulting

As the cannabis industry continues to grow, more entrepreneurs are seeking opportunities to set up shop as commercial growers. In this business, the hurdles can be high – and frequent – but the payoff is often worthwhile: Some 60% of wholesale cultivators report their business to be “very profitable” or “modestly profitable.”

Cannabis cultivation facilities often come with steep startup costs, often well into six figures and sometimes reaching seven. The buildings must be up to code, secure, and optimized for production. Whether you are starting from the ground up or remodeling an old warehouse, surround yourself with experienced professionals who can help you make the dozens of decisions that go into building a profitable facility.


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Understanding the Science and History of Cannabinoids

Cannabis Information

For thousands of years, healers around the world have used cannabis to help their patients. In more recent times, scientists have discovered the chemical properties and biological functions that make cannabis an effective treatment for ailments ranging from seizures to nausea to anxiety.

In the late 1800s, the first cannabinoid was isolated from a red oil extract of cannabis, but it wasn’t until the 1980s that researchers discovered cannabinoid receptors in the human body. This week, we’ll share an overview of what we know about cannabinoids and how they work so you have a high-level understanding of the science behind medical marijuana.


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Starting a Dispensary: How to Advertise Cannabis According to Your State

Cannabis Business Tips, Cannabis Laws

As anyone starting a dispensary knows, the dance between state and federal law is a delicate one that reaches into many aspects of the business, including advertising. Naturally, cannabis entrepreneurs want to promote their products, but it is illegal to advertise a Schedule 1 drug.

Cannabis marketing also involves multiple government agencies. The Federal Communications Commission grants licenses to radio and television broadcasters, which means they can take them away from station owners who violate federal law.


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Why Is So Much Cannabis Grown in Humboldt County?

Cannabis Information

With mountains, forests, and 110 miles of coastline, California’s Humboldt County could be a destination for its scenery alone. But a 1960s back-to-the-land movement planted the seeds, quite literally, for Humboldt County’s true claim to fame: America’s cannabis capital.

How Humboldt County’s Relationship With Cannabis Came to Be

In those days, San Francisco’s Haight-Ashbury was the center of the counterculture movement. (Time magazine calls it “Ground Zero for the Summer of Love.”) When a group of hippies decided to escape consumerism, pollution, and the Vietnam War and embrace a simpler way of life, the back-to-the-land movement was born. Many young people traveled north and settled in beautiful Humboldt County.

Since cannabis was an important part of the hippy culture, it was natural for these migrants to plant this crop next to the vegetables in their gardens. In the mid-1970s, a new growing technique called sinsemilla introduced seedless cannabis to the area. This new plant contained significantly more THC than regular cannabis, so growers were able to charge more for it. Humboldt, along with nearby Mendocino and Trinity Counties, became known as the Emerald Triangle, the largest cannabis-producing region in the country and the region that established some of America’s wealthiest small farmers.


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Yes on M, says LA Times

Cannabis on the Ballot


The Los Angeles Times has come out strongly in favor of Measure M on the March 7th ballot initiative. At SIVA, we wholeheartedly agree: Yes on M.

The Times says it best: "[Measure M] would give the City Council and mayor permission to repeal Proposition D — adopted by voters in 2013 to curb the spread of medical marijuana dispensaries — and to replace it with a new set of rules covering all aspects of the industry, from where marijuana businesses can locate and the hours they may operate to how they market their products."

We are in favor of Prop D shops getting licensed - they've put in the years of hard work and risk in a confusing regulatory environment. We also feel strongly that many others should also have the chance. The Los Angeles market is the largest market within the largest state market in the world. There is ample opportunity and market share for many qualified operators!

We look forward to an open and competitive marketplace in Los Angeles where the best products and services are allowed to succeed.

We also realize that many people have election-burn out, but this vote is very important for the future of our industry in Los Angeles. Please take a small amount of time to VOTE YES ON M.

It's not difficult to cast your ballot BY MAIL. Here are a few tips about voting for Measure M from the LA County Registrar:

Los Angeles County Registrar-Recorder/County Clerk

Voting by Mail in L.A. County

All voters in Los Angeles County have the option to vote by mail. A Vote by Mail (VBM) Ballot is mailed to voters, who can mail back the ballot or to drop off the ballot at a polling place on Election Day.

Please note VBM ballots postmarked by Election Day will be counted if received within three days by the Registrar-Recorder/County Clerk (California Senate Bill 29).

NOTE: The returned postage required for a Vote by Mail ballot is a single first-class stamp.

March 7, 2017 Consolidated Municipal and Special Elections

Online VBM Application

Paper VBM Application




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SIVA Cannabis Update: State-by-State

Cannabis in the News, Cannabis Laws, Cannabis on the Ballot

The_States_where_cannabis_is_legal_as_of_Jan_2017Here's a lighting-quick summary of a mere fraction of recent cannabis legislative activity across the US:

New Jersey: "N.J. migraine, chronic pain patients seek OK to use medical marijuana"

New Mexico: "Medical marijuana reforms clear New Mexico Senate"

Georgia: "Medical Marijuana Bill Clears Georgia Senate Working Group"

Wisconsin: "Wisc. State Senate Approves Marijuana Oil Legislation"

Florida: "Florida Officials Clash With Voters Over Medical Cannabis Rules"

Kansas: "Marijuana bill to be introduced in Kansas"

Virginia: "Marijuana Emerges As Virginia Campaign Issue"


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“Preparing Your Business for Trump” – MJ Business Magazine, featuring Avis Bulbulyan

Avis Bulbulyan, Cannabis Consulting, Cannabis in the News

LOGO_Marijuana_Business_MagazineCannabis business consultant and SIVA CEO Avis Bulbulyan is featured in the Feb. 2017 issue of Marijuana Business Magazine, "Preparing your Business for Trump":  

"As the calendar flipped to 2017, marijuana executives and investors had one question on their minds: What will happen to the cannabis sector under Donald Trump? It’s possible President Trump or someone in his administration has already said something about cannabis by the time you read this – or it might be a while until the new commander in chief gives any indication of how he’ll approach the marijuana industry. 

Regardless, there likely will be a hefty amount of uncertainty ahead, and many scenarios could play out.

We spoke at length with cannabis consultant Avis Bulbulyan as part of our extensive research for the report “Trump & the $5 Billion Marijuana Industry,” released in early January, to get his advice on how businesses should proceed and what might play out under a new administration.

Here are excerpts of that conversation, edited for length and clarity:

Read more at Marijuana Business Daily "Preparing Your Business for Trump"

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Cultivation Budget: Your Sharpest Tool Should Be Your Pencil

Avis Bulbulyan, Cannabis Business Tips, Cultivation

LOGO_Marijuana_Venture, Cultivation Budget articleAs cannabis growers know all too well, the cultivation budget process can be one of their biggest challenges. SIVA CEO Avis Bulbulyan has penned an important "Cannabis Economics 101" editorial in the January 2017 issue of Marijuana Venture. Here's a link to simple but essential advice about the necessity of making a comprehensive budget and sticking with it.

"... Cannabis growers ... have been waiting with bated breath for new opportunities to expand their businesses and get a piece of the multi-billion-dollar market opportunity. Many are excited to file applications for the limited number of licenses as soon as they become available.

"To score well in this competitive process, it will benefit entrepreneurs to spend this quiet period (before applications are released) sharpening their pencils, rather than their tools..."

"If you’re an experienced grower, this article may serve as a checklist. Whether you’ve been running a small indie grow and want to “go big,” or you’re setting up a first-time operation, you’ll likely have to raise some money. Investors will want to make sure you know how to grow, but they’ll also take a hard look at your numbers to ensure you know how to manage a business..."

READ MORE at Marijuana Venture...

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Does Medical Marijuana Kill Cancer Cells? The Truth About Cannabinoids

Cannabis Health, medical marijuana

Although cannabis has long been used to treat patients with cancer, scientists have a loftier goal in mind for the plant: curing certain forms of cancer entirely.

New cancer research is looking at cannabinoids, the chemical compounds found in cannabis. There are more than 60 different known cannabinoids, the most famous of which is tetrahydrocannabinol, or THC, the chemical component that causes users to feel high.

As scientists gain a better understanding about how cannabinoids affect cancer cells, they can develop medicines and medical treatments using concentrated amounts of these cancer-fighting compounds. Once the medicine is approved, cannabis manufacturing facilities can produce and distribute it to patients who need it.

Preclinical Studies Indicate Cannabinoids May Destroy Cancer Cells

Early research shows promise that specific cannabinoids can kill or damage cancer cells without harming normal cells in patients with liver cancer, lung cancer, or breast cancer.

Upon entering the body, cannabinoids bind to special cannabinoid receptors (part of the body’s endocannabinoid system), causing a reaction. Together, they help regulate body functions such as appetite, pain sensation, memory, and mood. This dynamic duo of cannabinoid and receptor may be the key to destroying cancer cells.


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Understanding the Physical & Chemical Properties of Cannabis

Cannabis Health, Cannabis Information

When it comes to cannabis research, scientists have only scratched the surface. There is much to be discovered about the resin, the cannabinoids, and the more than 400 chemical compounds found in each plant.

Researchers at universities, hospitals, and pharmaceutical companies are studying different cannabis strains at the molecular level to understand how its components work separately, together, and as the plant matter changes. This is no small feat considering the legalities and paperwork involved with handling a Schedule 1 drug.

As the cannabis industry evolves in the United States, we can expect to learn more about this versatile plant and its many uses. To get a general idea of what is happening in labs and classrooms across the country, here are some of the key components and properties of cannabis. Download our checklist that breaks down the physical and chemical properties of cannabis.

Cannabinoid Research from THCa to CBN

Medical scientists and drug manufacturers often seek to isolate the specific compounds that cause a desired effect, such as reducing nausea or stunting tumor growth. From there, a drug or treatment is developed that uses a concentrated amount of the compound. Once the drug is approved, cannabis manufacturing facilities begin producing these products for patients.

Many of today’s studies focus on the compounds that are present only in cannabis, which are known as cannabinoids. While there are 66 known cannabinoids, the compounds below are getting the most attention.

Tetrahydrocannabinolic Acid (THCa) – Before the cannabis plant is dried, it contains a cannabinoid called THCa. Unlike THC, THCa does not cause users to feel high. It does, however show potential in decreasing inflammation in patients with chronic lupus and is used to reduce seizures.

Tetrahydrocannabinol (THC) – This cannabinoid, also known as delta-9-tetrahydrocannabinol, occurs as the plant is dried and heated (e.g., smoked or cooked). THC is the ingredient that causes mind-altering effects in those who consume it. It also has therapeutic benefits, such as decreasing nausea and stimulating the appetite, which is helpful to cancer patients undergoing chemotherapy treatment. THC is also said to help patients with ALS, arthritis, chronic pain, fibromyalgia, multiple sclerosis, glaucoma, and Alzheimer’s disease. PTSD?

Cannabidiol (CBD) – Patients use CBD to relieve pain, prevent nausea, and reduce inflammation. Researchers are studying CBD as a treatment for mood disorders, Parkinson’s disease, schizophrenia, epilepsy, anxiety, and chronic pain.

Cannabichromene (CBC) – After THC, CBC is the second most concentrated cannabinoid found in cannabis. This antifungal, anti-inflammatory, antibiotic compound is said to fight bacteria, pain, depression, and migraines. Researchers are also studying whether CBC can stunt tumor growth in cancer patients.

Cannabinol (CBN) – When light and oxygen hit THC, CBN is created. CBN may even boost the effects of THC. This cannabinoid appears to be the key to disrupting seizures and spasms, and it can relieve the painful eye pressure caused by glaucoma. Scientists are considering CBN’s use as an antidepressant and sedative, too.

For the Botanist: Other Cannabis Plant Properties

In addition to cannabinoids, cannabis is comprised of these constituents, according to the International Association for Cannabis as Medicine (IACM):

  • 27 nitrogenous compounds
  • 18 amino acids
  • 3 proteins
  • 6 glycoproteins
  • 2 enzymes
  • 34 sugars and related compounds
  • 50 hydrocarbons
  • 7 simple alcohols
  • 13 aldehydes
  • 13 ketones
  • 21 simple acids
  • 22 fatty acids
  • 12 simple esters
  • 1 lactones
  • 11 steroids
  • 120 terpenes
  • 25 non-cannabinoid phenols
  • 21 flavonoids
  • 1 vitamins (A)
  • 2 pigments

While there is still much to learn about different cannabis strains, cannabis is already showing exciting potential to change the course of medical treatments and perhaps even eradicate certain conditions. It’s also clear that insights from these studies will make cannabis dispensary training vital for more informed purchases. At SIVA Enterprises, we are thrilled that cannabis is starting to get the attention – and the respect – it deserves.

SIVA Enterprises: Experts in Cannabis Business Development

SIVA Enterprises is a full-service business development firm that provides consulting, turnkey management, venture opportunities, and brand acquisitions and licensing to cannabis entrepreneurs across the country. Learn why we have the highest success rate of approved cannabis license applications in the United States. Contact SIVA at (818) 562-3362 or

physical and chemical properties of cannabis

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